Experience with tacrolimus in children with steroid-resistant nephrotic syndrome
نویسندگان
چکیده
منابع مشابه
Children with Steroid-resistant Nephrotic Syndrome: a Single-Center Study
Background and Aim: Steroid-resistant nephrotic syndrome (SRNS) accounts for 10%-20% of all cases of idiopathic nephrotic syndrome. These patients are at risk of developing end-stage renal disease. The aim of this study was to determine the demographic characteristics, renal biopsy findings, response to immunosuppressive treatment, and prognosis in pediatric patients with SRNS.Materials and Met...
متن کاملchildren with steroid-resistant nephrotic syndrome: a single-center study
background and aim: steroid-resistant nephrotic syndrome (srns) accounts for 10%-20% of all cases of idiopathic nephrotic syndrome. these patients are at risk of developing end-stage renal disease. the aim of this study was to determine the demographic characteristics, renal biopsy findings, response to immunosuppressive treatment, and prognosis in pediatric patients with srns.materials and met...
متن کاملNUP107 mutations in children with steroid-resistant nephrotic syndrome.
Background NUP107 is a novel gene associated with autosomal recessive steroid-resistant nephrotic syndrome (SRNS) with focal segmental glomerulosclerosis (FSGS) in children. The frequency of NUP107 mutations in children with SR-FSGS remains unknown. Methods Nine families with two siblings affected by childhood-onset SRNS or proteinuria were recruited. FSGS was confirmed by a kidney biopsy in ...
متن کاملEndothelial Dysfunction in Children with Steroid-Resistant Nephrotic Syndrome
Background: Steroid-resistant nephrotic syndrome (SRNS) is associated with early atherosclerosis because of comorbidities including persistent hyperlipidemia and hypertension. The aim of this study was to determine the incidence of abnormal carotid intima-media thickening (cIMT) as an early sign of atherosclerosis in a small group of children with SRNS. Methods: A total of 8 children with SRNS ...
متن کاملTreatment with Cyclophosphamide for steroid-resistant nephrotic syndrome in children.
The management of patients with steroid-resistant nephrotic syndrome remains difficult. We repport our experience with Cyclophosphamide therapy, in an attempt to compare the results between an oral protocol and two i.v. protocols. The complete and sustained general remission rate was 43.1%, which confirms the efficacy of the treatment, especially for children with minimal change nephrotic syndr...
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ژورنال
عنوان ژورنال: Pediatric Nephrology
سال: 2009
ISSN: 0931-041X,1432-198X
DOI: 10.1007/s00467-009-1220-z